Rasmussen Syndrome and Other Inflammatory Epilepsies

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Rasmussen Syndrome and Other Inflammatory Epilepsies.

An underlying immune basis is emerging in an increasing number of epileptic and encephalopathic syndromes. The immunopathological mechanisms may be categorized into antibody-mediated, T-cell cytotoxicity, and microglia-induced degeneration. The immune basis in Rasmussen syndrome is thought to be T-cell mediated. Antibodies to extracellular and intracellular epitopes are implicated in limbic and...

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Comparison of temporal lobe epilepsy with hippocampal sclerosis and temporal lobe epilepsies due to other etiologies

  Background: This study compares the clinical characteristics of patients with mesial temporal lobe epilepsy with hippocampal sclerosis (mTLE-HS) with those who have temporal lobe epilepsy (TLE) due to other etiologies.   Methods : In this retrospective study all patients with a clinical diagnosis of TLE were recruited in a referral outpatient epilepsy clinic at Shiraz University of Medical Sc...

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Language after Hemispherotomy in Rasmussen Syndrome

Investigators from Rothschild Foundation Hospital in Paris report language outcome in children after (left) dominant-hemisphere hemispherotomy for Rasmussen Syndrome.

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Rasmussen syndrome: An Argentinean experience in 32 patients

PURPOSE The aim of this study is to analyze the electroclinical features, treatment, and evolution of patients with Rasmussen syndrome (RS). MATERIALS AND METHODS We conducted a retrospective, descriptive study in 32 consecutive patients with RS followed between 1990 and 2012. RESULTS Twenty boys and 12 girls were included in the study. The mean and median ages at onset of the seizures were...

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Timing of surgery in rasmussen syndrome: is patience a virtue?

Rasmussen syndrome affects previously normal people and forever changes their lives and the lives of their families. Although understood as a probable autoimmune condition, medical treatment remains limited and surgery remains the only cure, although with inevitable functional consequences. Difficulties remain in deciding on the optimal timing of surgery. Here, we review data available to aid c...

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ژورنال

عنوان ژورنال: Seminars in Neurology

سال: 2015

ISSN: 0271-8235,1098-9021

DOI: 10.1055/s-0035-1552921